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Patient Information Series

What is Myocardial Infarction?

Otherwise known as a heart attack, myocardial infarction is due to sudden blockage of the blood supply to the heart. This results from  a crack in the wall of a diseased, hardened heart artery (coronary artery) which acts as an irritant setting up a clot which blocks off oxygen and nutrients to the heart muscle supplied by the artery. More than 110,000 deaths occur annually in England from coronary heart disease. 

What are the symptoms?

Severe sustained central chest pain which is felt as a tightness is the most common symptom. The pain may radiate to one or both arms, the jaw, upper abdomen or back and is constricting or suffocating in character. There may be associated nausea or vomiting, distress and anxiety, sweating and breathlessness. 

What is the treatment?

The key to survival is prompt transfer to hospital by ambulance with a crew trained to recognize the symptoms and perhaps initiate treatment.

The diagnosis is by clinical assessment, ECG and blood tests to check for elevated cardiac enzymes.

Treatment involves the use of drugs to control pain and nausea and administration of clot-bursting drugs (thrombolysis), which ideally should be given during the first hour. Aspirin is also beneficial and some patients may require cardiopulmonary resuscitation and defibrillation. In some instances urgent coronary artery balloon dilatation (angioplasty) may be performed. Unfortunately 35-40% of patients die within 24hours of onset of symptoms. 

What is the long - term care?

Effective medication after discharge from hospital include aspirin, b blockers, ACE-inhibitors and cholesterol lowering drugs (statins). Cardiac rehabilitation by lifestyle adjustments to diet, exercises, smoking and alcohol is recommended. Some survivors require angioplasty or coronary artery bypass graft operation(CABG). 

What are the risk factors for Coronary Disease?

Risk factors include age, sex, smoking, hypertension, diabetes, and high blood cholesterol. Check the Coronary Disease Risk section for more information and how to calculate your risk. 

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